vinca alkaloids

vinca alkaloids

Dictionary of molecular biology. 2004.

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  • vinca alkaloids — alkaloids produced by the Madagascar periwinkle, Vinca rosea; they are cytotoxic and cell cycle–specific for the M phase of cell division, acting by binding to tubulin, leading to arrest of cells in metaphase …   Medical dictionary

  • vinca alkaloid — n any of several alkaloids (as vinblastine and vincristine) obtained esp. from the rosy periwinkle * * * one of a group of antimitotic drugs (see cytotoxic drug) derived from the periwinkle (Vinca rosea). Vinca alkaloids, which are usually… …   Medical dictionary

  • vinca alkaloid — one of a group of antimitotic drugs (see also cytotoxic drug) derived from the periwinkle (Vinca rosea). Vinca alkaloids are used especially to treat leukaemias and lymphomas; they include vinblastine (Velbe), vincristine (Oncovin), and vindesine …   The new mediacal dictionary

  • vinca alkaloid — A type of drug that blocks cell growth by stopping mitosis (cell division). Vinca alkaloids interfere with microtubules (cellular structures that help move chromosomes during mitosis). They are used to treat cancer. A vinca alkaloid is a type of… …   English dictionary of cancer terms

  • vinca — vin·ca viŋ kə n PERIWINKLE * * * Vin·ca (vinґkə) [L. pervinca periwinkle] a genus of woody herbs of the family Apocynaceae, including periwinkles. V. miґnor L. is the common, or lesser, periwinkle. V. roґsea L. is the Madagascar periwinkle,… …   Medical dictionary

  • Vinca minor — plant Scientific classification Kingdom: Plantae …   Wikipedia

  • Vinca rosea — A species of myrtle (family Myrtaceae) used in various parts of the world as a home remedy; two active dimeric alkaloids obtained from this plant are vinblastine and vincristine. SYN: periwinkle …   Medical dictionary

  • Alkaloid, vinca — A medication in a class of anticancer drugs that inhibit cancer cell growth by stopping cell division (mitosis). The vinca alkaloids are also called antimitotic or antimicrotubule agents, or mitotic inhibitors. They include vinblastine,… …   Medical dictionary

  • Catharanthus alkaloids — SYN: Vinca alkaloids, under alkaloid …   Medical dictionary

  • Discovery and development of tubulin inhibitors — Tubulin inhibitors interfere directly with the tubulin system which is in contrast to those drugs acting on DNA for cancer chemotherapy. Microtubules play an important role in eukaryotic cells. Alpha and beta tubulin, the main components of… …   Wikipedia

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